■与普通人群相比,终末期肾病(ESKD)患者更容易受到病毒流行的影响,并且已知2019年冠状病毒病(COVID-19)的发病率和死亡率更高。我们确定了慢性血液透析(HD)中COVID-19的发病率和死亡率,腹膜透析(PD),和韩国的肾移植(KT)患者。
我们进行了一项回顾性队列研究,从2020年10月至2021年12月,从韩国国民健康保险服务获得了有关韩国ESKD成年人(年龄≥18岁)的数据。我们检查并比较了接受HD的患者中COVID-19相关感染和死亡的发生率,PD,还有KT.
■在所有ESKD患者中,85,018(68.1%)在HD上,PD为8,399(6.7%),KT和31,343(25.1%)。HD的COVID-19发病率为1.3%,PD为1.2%,KT为1.5%。HD的COVID-19死亡率为16.3%,PD为12.2%,KT为4.7%。与HD患者相比,PD患者的感染发生率较低(比值比[OR],0.76;95%置信区间[CI],0.607-0.93),但KT患者的感染风险显著较高(OR,1.28;95%CI,1.13-1.44)。与HD相比,PD患者的COVID-19相关死亡风险没有差异,但KT患者的风险显著较低(风险比,0.55;95%CI,0.35-0.88)。
■PD患者的COVID-19发病率低于HD患者,但是他们的死亡率没有什么不同。与HD相比,KT与COVID-19感染的风险更高,但死亡率更低。
UNASSIGNED: Patients with end-stage kidney disease (ESKD) are more susceptible to viral epidemics and are known to have higher incidence and death rates of coronavirus disease 2019 (COVID-19) compared to the general population. We determined COVID-19 incidence and mortality among chronic hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KT) patients in Korea.
UNASSIGNED: We conducted a retrospective cohort study and data regarding Korean ESKD adults (aged ≥18 years) were obtained from the National Health Insurance Service of Korea from October 2020 to December 2021. We examined and compared the incidence of COVID-19-related infections and deaths among the patients receiving HD, PD, and KT.
UNASSIGNED: Of all ESKD patients, 85,018 (68.1%) were on HD, 8,399 (6.7%) on PD, and 31,343 (25.1%) on KT. The COVID-19 incidence was 1.3% for HD, 1.2% for PD, and 1.5% for KT. COVID-19 mortality was 16.3% for HD, 12.2% for PD, and 4.7% for KT. PD patients had a lower incidence of infection compared to HD patients (odds ratio [OR], 0.76; 95% confidence interval [CI], 0.607-0.93), but KT patients had a significantly higher risk of infection (OR, 1.28; 95% CI, 1.13-1.44). Compared with HD, the risk of COVID-19-related death was not different for PD patients but was significantly lower for KT patients (hazard ratio, 0.55; 95% CI, 0.35-0.88).
UNASSIGNED: COVID-19 incidence was lower in PD patients than in HD patients, but mortality was not different between them. KT was associated with a higher risk of COVID-19 infection but lower mortality compared to HD.